What Triggers Autoimmune Conditions?

While the exact cause remains unclear, research points to a combination of genetic predisposition and immune dysregulation. Certain individuals, due to their genetic makeup, are more prone to developing autoimmune conditions, though not everyone with these genes will develop one. Autoimmune conditions also tend to run in families.

How the Immune System Goes Awry

The immune system protects against viruses, bacteria, and other foreign invaders. However, in some individuals, a trigger like a common infection or trauma can cause the immune system to overreact. Instead of calming down after the threat is gone, the inflammation continues, leading to immune dysregulation.

Chronic Inflammation and Damage

In autoimmune conditions, the immune system mistakenly identifies parts of the body—joints, skin, or organs—as foreign and attacks them. This leads to chronic inflammation, which, if left unchecked, can result in lasting damage, disability, and other severe health issues.

The Role of Inflammation

While acute inflammation is a normal response to injury or infection, in autoimmune patients, the inflammation becomes chronic and uncontrolled, driving the disease process.

Understanding and managing this inflammation is key to treating autoimmune conditions effectively.