Fatigue is one of the most common symptoms reported by people living with rheumatoid arthritis (RA). Understanding the underlying causes is key to managing it effectively.

1️⃣ Chronic Inflammation
Ongoing inflammation from RA can drain energy levels, making daily tasks feel exhausting. Even when inflammation is managed, fatigue may persist.

2️⃣ Chronic Pain
Pain from joint damage or irritation can be physically and mentally draining. It can also disrupt sleep, further contributing to fatigue.

3️⃣ Medication Side Effects
RA medications are effective at controlling inflammation but can have side effects like anemia, gastrointestinal issues, or general fatigue, especially with drugs like methotrexate.

4️⃣ Cardiovascular Risks
RA patients are at higher long-term risk for early atherosclerotic disease, including heart attacks and strokes. Persistent fatigue may signal the need for cardiovascular screening.

Other Contributing Factors

• Metabolic issues from long-term prednisone use, including adrenal insufficiency and high blood sugar
• Low vitamin D or B12
• Obstructive sleep apnea
• Depression or mental health challenges

Conclusion
Fatigue in RA is real and multifactorial. If you experience persistent exhaustion, consult your physician to identify underlying causes and receive appropriate treatment.

📹 Watch the full video to learn more from Dr. Siddharth Tambar, expert in rheumatology and regenerative medicine.