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Understanding Hypermobility: A Case Study

Hypermobility is a condition affecting the joints, tendons, and ligaments, where ligaments are slightly looser than normal. This looseness leads to joint instability, resulting in a higher risk of injuries, a likelihood of developing osteoarthritis long-term, and persistent chronic pain.

A Young Patient’s Journey

Today, a young woman was referred for an evaluation due to persistent joint pain. She had a family history of psoriasis, and someone suspected she might have psoriatic arthritis. After a thorough examination, which included lab work and imaging, there were no clear signs of inflammation. This ruled out psoriatic arthritis or any other inflammatory arthritis.

Diagnosing Hypermobility Syndrome

Upon further evaluation, it was determined that the patient actually has hypermobility syndrome. She also has a family history of Ehlers-Danlos Syndrome (EDS), a genetic condition associated with hypermobility. Genetic testing will confirm if she has EDS, but for now, the focus is on managing her hypermobility.

Treating Hypermobility

This patient leads an active lifestyle and follows appropriate strengthening exercises and supplements. Despite her efforts, she continues to suffer from chronic lower back, sacroiliac joint pain, and shoulder discomfort. The next step in her treatment plan will be platelet-rich plasma therapy, specifically targeting her hypermobility.

A Lesson in Differential Diagnosis

This case illustrates the importance of considering all possibilities when diagnosing a condition. While inflammatory arthritis was suspected, the real issue was hypermobility. Identifying this allowed for the correct treatment to be administered, which will make a meaningful difference in this patient’s life.


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